@booklet {279, title = {Techniques and systems for local independent failure domains}, year = {2017}, abstract = {

Techniques and systems are described for enabling local independent failure domains in a host server or datacenter environment. Included is a locally-attached independent failure device (LA-IFD) with an independent data buffer and a local communications bus for attaching to a host server. Techniques for a communications protocol between the LA-IFD and its host server are provided, including: receiving a request to write a data segment to persistent storage; synchronously storing the data segment in a buffered data segment at the LA-IFD and initiating an asynchronous update of the data segment at a remote storage system; sending a write acknowledgement indicating completion to the requestor; and, after receiving a completion notification from the remote storage system, removing the buffered data segment from the LA-IFD. In some cases, techniques allow a host server and LA-IFD pair to monitor one another for failures and implement a modified protocol in the event of unavailability.

}, keywords = {other}, author = {Rangaswami, Raju and Biookaghazadeh, Saman and Lyons, Steven} } @article {277, title = {MemBuilder: a web-based graphical interface to build heterogeneously mixed membrane bilayers for the GROMACS biomolecular simulation program}, journal = {Bioinformatics}, volume = {30}, year = {2013}, pages = {439{\textendash}441}, abstract = {

Motivation:\ Molecular dynamics (MD) simulations have had a profound impact on studies of membrane proteins during past two decades, but the accuracy of MD simulations of membranes is limited by the quality of membrane models and the applied force fields. Membrane models used in MD simulations mostly contain one kind of lipid molecule. This is far from reality, for biological membranes always contain more than one kind of lipid molecule. Moreover, the lipid composition and their distribution are functionally important. As a result, there is a necessity to prepare more realistic lipid membranes containing different types of lipids at physiological concentrations.

Results:\ To automate and simplify the building process of heterogeneous lipid bilayers as well as providing molecular topologies for included lipids based on both united and all-atom force fields, we provided MemBuilder as a web-based graphical user interface.

Availability and implementation:\ MemBuilder is a free web server available\ 

}, keywords = {other}, author = {Ghahremanpour, Mohammad Mehdi and Arab, Seyed Shahriar and Biookaghazadeh, Saman and Zhang, Jin and van der Spoel, David} }